Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
There are many steps on the road from
discovery of an anticancer drug to securing its final approval by the
Food and Drug Administration. In this thoroughly updated and expanded
second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics,
leading investigators synthesize an invaluable overview of the
experimental and clinical processes of anticancer drug development,
creating a single indispensable reference that covers all the steps from
the identification of cancer-specific molecular targets to screening
techniques and the development and validation of bioanalytical methods
to clinical trial design and all phases of clinical trials. The authors
have included new material on phase 0 trials in oncology, organ
dysfunction trials, drug formulations and their impact on anticancer
drug PK/PD including strategies to improve drug delivery,
pharmacogenomics and cancer therapy, high throughput platforms in drug
metabolism and transport pharmacogenetics, imaging in drug development
and nanotechnology in cancer.
Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs.
Ebook format: PDFAuthoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs.
- Road map to anticancer drug development from discovery to NDA submission
- Discussion of molecular targets and preclinical screening
- Development and validation of bioanalytical methods
- Chapters on clinical trial design and phase 0, I, II, III clinical trials
- Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents
- Review of the drug development process from both laboratory and clinical perspectives
- New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development
Ebook page: 828
File size: 10.90 MB
$75.00
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